They then added the Spike gene to the adenovirus vector | Where is the Oxford-AstraZeneca vaccine made? 351 coronavirus variant in young South African adults |
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Safety and efficacy of the ChAdOx1 nCoV-19 vaccine AZD1222 against SARS-CoV-2: an interim analysis of four randomized controlled trials in Brazil, South Africa, and the UK | The Lancet, 397 10269 : 99-111 |
It just trains our immune system to quickly recognize that part of the virus | AZD1222 US Phase III trial met primary efficacy endpoint in preventing COVID-19 at interim analysis |
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So they took an adenovirus that normally infects chimpanzees, and genetically altered it so it can no longer replicate or cause disease |
That way when we are infected with , we can mount an effective immune response against it.
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